7 deaths in UK among AstraZeneca jab recipients after blood clots: Medical regulator

The UK medical regulator mentioned Saturday that out of 30 individuals who suffered uncommon blood clots after receiving the Oxford-AstraZeneca vaccine, seven have died.

The British acknowledgement of deaths comes as a number of European nations have paused the use of the AstraZeneca jab over a potential link to blood clots.

The UK’s Medicines and Healthcare merchandise Regulatory Agency (MHRA) mentioned in a press release that “Out of the 30 reports up to and including 24 March, sadly 7 have died.”

The studies of thrombosis, submitted by medics or members of the general public by way of a authorities web site, got here after 18.1 million doses of the vaccine had been administered in the nation.

Most of the circumstances (22) have been a uncommon clotting situation known as cerebral venous sinus thrombosis. Eight circumstances noticed folks undergo different sorts of thrombosis mixed with low ranges of blood platelets, which assist blood clot.

There have been no studies of blood clots from the Pfizer-BioNTech vaccine, the UK regulator mentioned, including that “our thorough review into these reports is ongoing”.

But MHRA chief government Dr June Raine careworn that the advantages far outweighed any dangers. “The public should continue to get their vaccine when invited to do so,” she mentioned.


Both the MHRA and European Medicines Agency (EMA) say no causal hyperlink has but been established between the blood clotting case and the AstraZeneca vaccine.

But rising issues have prompted various nations to pause rollout of the vaccine or restrict it to older folks because of the comparatively younger age of those that suffered blood clots.

Netherlands on Friday halted vaccinations with the AstraZeneca jab for folks underneath the age of 60 after 5 new circumstances among youthful girls, considered one of whom died.

Germany has suspended the use of the vaccine for those under 60 after 31 cases of blood clots, most of them among youthful and middle-aged girls.

Plenty of different nations together with France have imposed an analogous age restrictions, whereas Denmark and Norway have suspended all use of the vaccine.

The European Medicines Agency (EMA), which just like the World Health Organization previously declared the AstraZeneca vaccine safe, is anticipated to announce up to date recommendation on the difficulty on April 7.

It mentioned Wednesday that there had been 62 circumstances worldwide of cerebral venous sinus thrombosis, 44 of them in the European Economic Area, which incorporates the European Union, Iceland, Liechtenstein and Norway.

This determine didn’t embrace all Germany’s circumstances, nevertheless.

More than 9.2 million AstraZeneca jabs have been administered in the area.

The EMA mentioned it believes the vaccine is secure and that specialists have discovered no particular threat elements corresponding to age, gender or medical historical past.


Paul Hunter, a medical microbiologist at Britain’s University of East Anglia, informed AFP that he had initially thought the hyperlink between vaccination and blood clots was more likely to be a “random association”.

As proof mounts of clusters in separate nations, “the load of proof is now wanting in direction of Oxford-AstraZeneca actually being the cause of these adverse events“, he mentioned.

Nevertheless, the danger for the unvaccinated of dying from Covid is “substantially greater,” he mentioned.

A spokeswoman for AstraZeneca informed AFP that affected person security is its “highest priority”.

UK, EU and World Health Organization regulatory our bodies have concluded that the advantages “significantly outweigh the risks across all adult age groups”, she said.

AstraZeneca mentioned final month following US effectivity trials that its vaccine is 76 % efficient at stopping the illness. It additionally mentioned knowledge for the EU and the UK confirmed no elevated threat of blood clots.

The UK has administered greater than 31 million first vaccine doses, utilizing each the Oxford-AstraZeneca and the Pfizer-BioNTech jabs. People can not select which one they get.

The UK in June 2020 ordered 100 million doses of the Oxford-AstraZeneca vaccine and supported its improvement. It additionally ordered 30 million doses of the Pfizer-BioNTech vaccine the identical 12 months.

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