Self-medication can increase Covid severity, warn doctors

With the unavailability of Covid emergency therapy throughout the nation resulting from a surge in circumstances, the problem of self-medication has change into a speaking level. Doctors have, nonetheless, very strongly warned towards this and stated self-medication can increase severity in Covid circumstances.

Popping antivirals, steroids and antibiotics in addition to injecting antivirals like remdesivir with out consulting a physician can result in the severity in Covid-19, doctors at Post Graduate Institute of Medical Education and Research (PGIMER) have warned.

Professor GD Puri, Head Department of Anaesthesia and Intensive Care, Dean teachers at PGI, Chandigarh stated, “Whenever a patient tests positive for Covid-19 there is a fear in his mind. The patient starts running around for drugs to get rid of the Covid-19.”

“Unfortunately there is a lot of misinformation about the drugs. There are certain drugs that may cause harm. Drugs like steroids and unnecessary use of Remdesivir, Tocilizumab and Itolizumab can prove harmful. Rather than helping the patient, it can increase the severity of the disease,” he stated.


Professor Puri stated that greater than 80 per cent of people that check constructive for Covid-19 might not require any remedy. Only 10 to fifteen per cent of sufferers would require paracetamol in addition to shut monitoring of the oxygen saturation stage.

Whenever a Covid-19 affected person reaches the emergency facility of a Covid-care facility at PGI Chandigarh, he’s requested to take a five-minute stroll. He is just hospitalised if the oxygen ranges drop beneath 94.

“The major problem in Covid-19 is the lung involvement which leads to the dropping of oxidation. This can simply be measured by a simple oximeter. If you keep monitoring the saturation and if the saturation is at baseline there is no need to worry,” he stated.

Professor Puri stated if the saturation doesn’t drop from the traditional 99 to 97 after strolling that signifies that the lung involvement isn’t important.


Professor GD Puri stated a CT scan can solely reveal lung an infection however can’t diagnose Covid-19 if the virus has not reached the lungs.

“Unfortunately some people believe that CT scan can diagnose Covid-19 which is totally wrong. CT scan may not show anything pertaining to Covid. Yes CT scan can show something if there is a lung involvement,” he stated.


Doctors at PGI Chandigarh have advisable considered use of steroids that too underneath the supervision of a specialist. Case research achieved by PGI have revealed that many sufferers have been popping and injecting antivirals and steroids on their very own which resulted within the severity of the illness.

“Steroids Can increase the replication of the virus in the body. If it is given in the early stages it can increase the severity of the damage caused by the virus. The right time is when the replication of the virus in the body is over,” Professor Puri stated.

Studies achieved by PGI have revealed that if steroids are given earlier than the saturation begins dropping it can increase the mortality and morbidity within the affected person.

Steroids ought to solely be given when the affected person’s saturation stage begins dropping from a traditional of 97 to beneath 94.

“That is the time we should start administering the steroids,” he stated.

Prof Puri additionally suggested to not use steroids even when the C-reactive protein (CRP) stage is larger as there may very well be many causes for the increase. CRP check is a blood check marker for irritation within the physique.

“Steroids should be avoided in the first week of the infection. These drugs should be given after the first week. When the fever is high and CT scan is showing some changes and CRP is high. Avoid using steroids even on the 9th or 10th day of the disease,” Professor Puri stated.


Remdesivir is a drug that’s used within the replication part of the virus, and it’s only given to the high-risk sufferers
with hypoxia.

“Administering this drug may not benefit the patient if he or she is on a ventilator,” Professor Puri stated.

Similarly, administering remdesivir when the affected person is at house is rarely useful.

“This drug has not shown any increase in the possibility of survival in patients admitted in hospital. It is only helpful in decreasing the stay in the hospital,” he stated.


Remdesivir needs to be given to hospitalised sufferers underneath the supervision of the physician that too after the requisite checks of the liver and renal operate.

Antiviral medicine like remdesivir should not advisable for sufferers identified with liver dysfunction. Similarly, remdesivir needs to be prevented if the renal operate check reveals a excessive stage of creatinine.

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